DETAILED NOTES ON ABBV-744 BRD4 INHIBITOR MECHANISM OF ACTION

The present work examined the potential of making use of ARV-825 and ABBV-744 to increase the effectiveness of tamoxifen or fulvestrant in addition palbociclib. ARV-825 was effective in both of those p53 wild-form (WT) breast tumor cells As well as in cells missing purposeful p53 possibly alone or in combination with tamoxifen, although the effecti